KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK1
All Species:
47.58
Human Site:
S248
Identified Species:
80.51
UniProt:
P28482
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28482
NP_002736.3
360
41390
S248
L
G
I
L
G
S
P
S
Q
E
D
L
N
C
I
Chimpanzee
Pan troglodytes
XP_510921
379
43006
S265
L
G
I
L
G
S
P
S
Q
E
D
L
N
C
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860750
375
42862
S248
L
G
I
L
G
S
P
S
Q
E
D
L
N
C
I
Cat
Felis silvestris
Mouse
Mus musculus
Q63844
380
43048
S266
L
G
I
L
G
S
P
S
Q
E
D
L
N
C
I
Rat
Rattus norvegicus
P63086
358
41257
S246
L
G
I
L
G
S
P
S
Q
E
D
L
N
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989481
368
41924
S256
L
G
I
L
G
S
P
S
Q
E
D
L
N
C
I
Frog
Xenopus laevis
P26696
361
41238
S251
L
G
I
L
G
S
P
S
Q
E
D
L
N
C
I
Zebra Danio
Brachydanio rerio
NP_878308
369
42057
S257
L
G
I
L
G
S
P
S
Q
E
D
L
N
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40417
426
49103
S311
L
G
V
L
G
S
P
S
R
D
D
L
E
C
I
Honey Bee
Apis mellifera
XP_393029
371
42705
S250
L
G
V
L
G
S
P
S
P
E
D
L
E
C
I
Nematode Worm
Caenorhab. elegans
P39745
444
50644
S319
L
A
V
V
G
S
P
S
N
A
D
L
Q
C
I
Sea Urchin
Strong. purpuratus
NP_999813
369
42176
S254
L
G
V
L
G
S
P
S
Q
D
D
L
K
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
D264
T
E
L
I
G
S
P
D
D
S
S
L
G
F
L
Baker's Yeast
Sacchar. cerevisiae
P16892
353
40754
H243
F
G
I
I
G
T
P
H
S
D
N
D
L
R
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
N.A.
96
N.A.
83.4
99.1
N.A.
N.A.
97.2
95.8
92.1
N.A.
67.8
81.9
64.4
79.4
Protein Similarity:
100
85.4
N.A.
96
N.A.
89.2
99.4
N.A.
N.A.
97.5
97.2
94.5
N.A.
74.6
86.7
70.9
84.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
73.3
80
60
80
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
93.3
86.6
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.4
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
8
% C
% Asp:
0
0
0
0
0
0
0
8
8
22
86
8
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
65
0
0
15
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
86
0
0
100
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
65
15
0
0
0
0
0
0
0
0
0
0
86
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
86
0
8
79
0
0
0
0
0
0
0
93
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
0
58
0
0
% N
% Pro:
0
0
0
0
0
0
100
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
65
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
93
0
86
8
8
8
0
0
0
0
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
29
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _